Ariad drug proves effective in curbing chronic leukemia in study












(Reuters) – An experimental leukemia drug from Ariad Pharmaceuticals Inc eliminated the cancer from the bone marrow of nearly half of patients with a chronic form of the disease who had stopped responding to other drugs, according to a 12-month follow-up of a pivotal drug trial.


The trial of the drug, ponatinib, which involved 444 patients, including 267 with chronic myeloid leukemia who had previously been treated with older drugs, also showed that 56 percent of chronic patients achieved the study’s goal of a “major response,” meaning the disease had nearly disappeared from the bone marrow.












Ariad earlier this year presented interim results from the trial, and U.S. Food and Drug Administration agreed in October to an expedited review. The agency is slated to decide by March 27 whether to approve ponatinib.


“We expect FDA approval sometime in the first quarter,” said Tim Clackson, Ariad’s chief scientific officer. He said the company is prepared to immediately launch sales of the drug. “We believe the overall trial data suggests activity in all forms of resistant disease.”


Ponatinib is designed to target an abnormal tyrosine kinase that is closely associated with chronic myeloid leukemia and Philadelphia chromosome positive acute lymphoblastic leukemia.


Ariad is also testing the drug in newly diagnosed CML patients. Final results from that trial are expected at the end of 2014, but an interim analysis will occur after half of the trial patients are enrolled, Clackson said.


Around 5,000 U.S. patients are diagnosed with CML each year, and about 2,500 patients will become resistant to their treatment, according to Ariad.


(Reporting By Deena Beasley; Editing by Leslie Adler)


Health News Headlines – Yahoo! News


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Alexander: No triple dip slump















Chief Secretary to the Treasury Danny Alexander: “It is a longer and harder road… but we are making progress”



Britain is not heading for a triple dip recession, Chief Secretary to the Treasury Danny Alexander has said.


Last week, the Office for Budget Responsibility (OBR) forecast that the economy was set to shrink in the final three months of 2012.


Mr Alexander said he accepted this, but added “steady growth” in 2013 meant the UK would avoid another recession.


He said the road to economic recovery was being “longer and harder” than expected, but progress had been made.


The OBR growth forecasts show that despite the UK economy’s return to growth in the three months from July to September, in the final quarter the economy will shrink again by 0.1%, before growth returns in 2013.


The UK would experience a triple dip recession if it had two quarters or more of negative growth before the economy had fully recovered from the 2008 recession.


It experienced a double dip recession earlier this year, with three quarters of negative growth between the end of 2011 and the middle of 2012.


‘Uncertain world’


Asked on the BBC’s Andrew Marr Show whether he thought the UK would face a triple dip recession, Mr Alexander said: “The OBR forecast that the final quarter of this year would be negative, but that we would see positive growth slowly returning in every quarter of next year.


“That would suggest that we’re not going to have that happening. But it is an uncertain world out there.


“We’re seeing continuing problems in the eurozone, but I’m happy to rest on the OBR’s forecast, which is a bounce-back from the Olympic boost we saw in the third quarter causing a small negative in the final quarter of this year, but then steady growth slowly starting to return next year and the year after that.”


However, Mr Alexander’s Liberal Democrat colleague Business Secretary Vince Cable was more cautious.


He told the Observer there was “certainly a risk” of the UK going back into its third recession since 2008, although it is more likely the economy will “continue bumping along the bottom”.


Mr Alexander said slow growth in the eurozone and the “weight of the broken banking system in the United Kingdom” were weighing down the economy.


This meant the economic recovery was “a longer and harder road” than expected, but he said: “We are making progress and I think we are going to get there”.


Spending review


He said he would continue to protect the NHS budget and schools spending, as he looks to save an additional £10bn before the next election.


It follows a warning from the Institute for Fiscal Studies (IFS) that unprotected government departments could face could cuts of more than 30% following the Autumn Statement.


It said further welfare cuts and tax rises “must be on the cards” to make the government’s numbers add up if the NHS and welfare continue to be protected.


Mr Alexander said additional savings to be made in 2015-16 will be “at the same pace” as departments have had in recent years.


“I think we’re right not to chase our debt target, but instead to continue to do this in a steady way,” he added.


Decisions on spending for after the next election, and whether to continue to protect the NHS budget, would be set out in party manifestos, he said.


The next spending review, which will set out future departmental spending, is expected to be announced in the first half of next year.


BBC News – Business


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Peru’s capital highly vulnerable to major quake












LIMA, Peru (AP) — The earthquake all but flattened colonial Lima, the shaking so violent that people tossed to the ground couldn’t get back up. Minutes later, a 50-foot (15-meter) wall of Pacific Ocean crashed into the adjacent port of Callao, killing all but 200 of its 5,000 inhabitants. Bodies washed ashore for weeks.


Plenty of earthquakes have shaken Peru‘s capital in the 266 years since that fateful night of Oct. 28, 1746, though none with anything near the violence.












The relatively long “seismic silence” means that Lima, set astride one of the most volatile ruptures in the Earth’s crust, is increasingly at risk of being hammered by a one-two, quake-tsunami punch as calamitous as what devastated Japan last year and traumatized Santiago, Chile, and its nearby coast a year earlier, seismologists say.


Yet this city of 9 million people is sorely unprepared. Its acute vulnerability, from densely clustered, unstable housing to a dearth of first-responders, is unmatched regionally. Peru’s National Civil Defense Institute forecasts up to 50,000 dead, 686,000 injured and 200,000 homes destroyed if Lima is hit by a magnitude-8.0 quake.


“In South America, it is the most at risk,” said architect Jose Sato, director of the Center for Disaster Study and Prevention, or PREDES, a non-governmental group financed by the charity Oxfam that is working on reducing Lima’s quake vulnerability.


Lima is home to a third of Peru’s population, 70 percent of its industry, 85 percent of its financial sector, its entire central government and the bulk of international commerce.


“A quake similar to what happened in Santiago would break the country economically,” said Gabriel Prado, Lima’s top official for quake preparedness. That quake had a magnitude of 8.8.


Quakes are frequent in Peru, with about 170 felt by people annually, said Hernando Tavera, director of seismology at the country’s Geophysical Institute. A big one is due, and the chances of it striking increase daily, he said. The same collision of tectonic plates responsible for the most powerful quake ever recorded, a magnitude-9.5 quake that hit Chile in 1960, occurs just off Lima’s coast, where about 3 inches of oceanic crust slides annually beneath the continent.


A 7.5-magnitude quake in 1974 a day’s drive from Lima in the Cordillera Blanca range killed about 70,000 people as landslides buried villages. Seventy-eight people died in the capital. In 2007, a 7.9-magnitude quake struck even closer, killing 596 people in the south-central coastal city of Pisco.


A shallow, direct hit is the big danger.


More than two in five Lima residents live either in rickety structures on unstable, sandy soil and wetlands that amplify a quake’s destructive power or in hillside settlements that sprang up over a generation as people fled conflict and poverty in Peru’s interior. Thousands are built of colonial-era adobe.


Most quake-prone countries have rigorous building codes to resist seismic events. In Chile, if engineers and builders don’t adhere to them they can face prison. Not so in Peru.


“People are building with adobe just as they did in the 17th century,” said Carlos Zavala, director of Lima’s Japanese-Peruvian Center for Seismic Investigation and Disaster Mitigation.


Environmental and human-made perils compound the danger.


Situated in a coastal desert, Lima gets its water from a single river, the Rimac, which a landslide could easily block. That risk is compounded by a containment pond full of toxic heavy metals from an old mine that could rupture and contaminate the Rimac, said Agustin Gonzalez, a PREDES official advising Lima’s government.


Most of Lima’s food supply arrives via a two-lane highway that parallels the river, another potential chokepoint.


Lima’s airport and seaport, the key entry points for international aid, are also vulnerable. Both are in Callao, which seismologists expect to be scoured by a 20-foot (6-meter) tsunami if a big quake is centered offshore, the most likely scenario.


Mayor Susana Villaran’s administration is Lima’s first to organize a quake-response and disaster mitigation plan. A February 2011 law obliged Peru’s municipalities to do so. Yet Lima’s remains incipient.


“How are the injured going to be attended to? What is the ability of hospitals to respond? Of basic services? Water, energy, food reserves? I don’t think this is being addressed with enough responsibility,” said Tavera of the Geophysical Institute.


By necessity, most injured will be treated where they fall, but Peru’s police have no comprehensive first-aid training. Only Lima’s 4,000 firefighters, all volunteers, have such training, as does a 1,000-officer police emergency squadron.


But because the firefighters are volunteers, a quake’s timing could influence rescue efforts.


“If you go to a fire station at 10 in the morning there’s hardly anyone there,” said Gonzalez, who advocates a full-time professional force.


In the next two months, Lima will spend nearly $ 2 million on the three fire companies that cover downtown Lima, its first direct investment in firefighters in 25 years, Prado said. The national government is spending $ 18 million citywide for 50 new fire trucks and ambulances.


But where would the ambulances go?


A 1997 study by the Pan American Health Organization found that three of Lima’s principal public hospitals would likely collapse in a major quake, but nothing has been done to reinforce them.


And there are no free beds. One public hospital, Maria Auxiliadora, serves more than 1.2 million people in Lima’s south but has just 400 beds, and they are always full.


Contingency plans call for setting up mobile hospitals in tents in city parks. But Gonzalez said only about 10,000 injured could be treated.


Water is also a worry. The fire threat to Lima is severe — from refineries to densely-backed neighborhoods honeycombed with colonial-era wood and adobe. Lima’s firefighters often can’t get enough water pressure to douse a blaze.


“We should have places where we can store water not just to put out fires but also to distribute water to the population,” said Sato, former head of the disaster mitigation department at Peru’s National Engineering University.


The city’s lone water-and-sewer utility can barely provide water to one-tenth of Lima in the best of times.


Another big concern: Lima has no emergency operations center and the radio networks of the police, firefighters and the Health Ministry, which runs city hospitals, use different frequencies, hindering effective communication.


Nearly half of the city’s schools require a detailed evaluation to determine how to reinforce them against collapse, Sato said.


A recent media blitz, along with three nationwide quake-tsunami drills this year, helped raise consciousness. The city has spent more than $ 77 million for retention walls and concrete stairs to aid evacuation in hillside neighborhoods, Prado said, but much more is needed.


At the biggest risk, apart from tsunami-vulnerable Callao, are places like Nueva Rinconada.


A treeless moonscape in the southern hills, it is a haven for economic refugees who arrive daily from Peru’s countryside and cobble together precarious homes on lots they scored into steep hillsides with pickaxes.


Engineers who have surveyed Nueva Rinconada call its upper reaches a death trap. Most residents understand this but say they have nowhere else to go.


Water arrives in tanker trucks at $ 1 per 200 liters (52 gallons) but is unsafe to drink unless boiled. There is no sanitation; people dig their own latrines. There are no streetlamps, and visibility is erased at night as Lima’s bone-chilling fog settles into the hills.


Homes of wood, adobe and straw matting rest on piled-rock foundations that engineers say will crumble and rain down on people below in a major quake.


A recently built concrete retaining wall at the valley’s head lies a block beneath the thin-walled wood home of Hilarion Lopez, a 55-year-old janitor and community leader. It might keep his house from sliding downhill, but boulders resting on uphill slopes could shake loose and crush him and his neighbors.


“We’ve made holes and poured concrete around some of the more unstable boulders,” he says, squinting uphill in a strong late morning sun.


He’s not so worried if a quake strikes during daylight.


“But if I get caught at night? How do I see a rock?”


___


Associated Press writer Franklin Briceno contributed to this report.


___


Frank Bajak on Twitter: http://twitter.com/fbajak


Latin America News Headlines – Yahoo! News


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Red Hat divulgará los resultados del tercer trimestre del año fiscal 2013 a través de un webcast












Red Hat Inc. (NYSE: RHT), proveedor líder mundial de soluciones de código abierto, analizará los resultados del tercer trimestre del año fiscal 2013 el jueves, 20 de diciembre de 2012, a partir de las 5:00 p. m., hora del Este.


Se puede acceder a un webcast en vivo en la página de Relaciones con los Inversores de Red Hat en http://investors.redhat.com y la reproducción se encontrará disponible a partir de aproximadamente dos horas luego de finalizados los eventos en vivo.












Acerca de Red Hat, Inc.


Red Hat es el proveedor líder mundial de soluciones de software de código abierto; utiliza un enfoque basado en la comunidad para tecnologías confiables y de alto rendimiento en la nube, Linux, middleware, almacenamiento y virtualización. Red Hat también ofrece servicios galardonados de consultoría asistencia y capacitación. Como centro de conectividad de una red global de empresas, socios y comunidades de código abierto, Red Hat ayuda a crear tecnologías relevantes e innovadoras que liberan recursos para el crecimiento y preparan a los clientes para el futuro de la tecnología de la información. Obtenga más información en: http://www.redhat.com.


Declaraciones a futuro


Ciertas declaraciones del presente comunicado de prensa pueden constituir “declaraciones a futuro” dentro del significado de la Ley de Reforma de Litigios Sobre Valores Privados (Private Securities Litigation Reform Act) de los EE. UU. de 1995. Las declaraciones a futuro ofrecen expectativas actuales de eventos futuros en base a determinados supuestos e incluyen cualquier declaración que no se relaciona directamente con cualquier hecho actual o histórico. Los resultados reales pueden diferir sustancialmente de los indicados por dichas declaraciones a futuro, como resultado de varios factores importantes, incluso: riesgos relacionados con retrasos o reducciones en el gasto en tecnología de la información; los efectos de la consolidación del sector; la capacidad de la Compañía de competir en forma eficaz; la incertidumbre y los resultados adversos en litigios y acuerdos relacionados; la integración de adquisiciones y la capacidad de comercializar en forma exitosa las tecnologías y productos adquiridos; la incapacidad de proteger adecuadamente la propiedad intelectual de la Compañía y el posible incumplimiento o violación de reclamaciones de licencia o relacionadas con la propiedad intelectual de terceros; la capacidad de entregar y estimular la demanda de nuevos productos e innovaciones tecnológicas en forma oportuna; los riesgos relacionados con la vulnerabilidad de la seguridad de datos y de información; la gestión ineficaz de, y control sobre las operaciones internacionales y el crecimiento de la Compañía; las fluctuaciones en las tasas de cambio; y cambios en el personal clave y una dependencia del mismo, así como otros factores presentes en nuestro más reciente Informe Trimestral en el formulario 10-Q (copias del cual se encuentran disponibles en el sitio Web de la Comisión de Bolsa y Valores en http://www.sec.gov), incluidos los que se encuentran en el título “Factores de riesgo” y “Análisis y Discusiones de la Gerencia sobre Condiciones Financieras y Resultados de Operaciones”. Además de estos factores, el desempeño futuro real, y los resultados pueden diferir sustancialmente debido a más factores generales que incluyen (entre otros) las condiciones generales del mercado y de la industria y las tasas de crecimiento, las condiciones económicas y políticas, los cambios en las políticas públicas y gubernamentales y el impacto de los desastres naturales como terremotos e inundaciones. Las declaraciones a futuro incluidas en este comunicado de prensa representan las opiniones de la Compañía a la fecha de este comunicado de prensa y estas ideas podrían cambiar. Sin embargo, si bien la Compañía puede elegir actualizar estas declaraciones a futuro en algún momento, la Compañía en forma específica renuncia a cualquier obligación de hacerlo. No debe confiar en estas declaraciones a futuro como si representaran las opiniones de la empresa a partir de cualquier fecha posterior de la fecha de este comunicado de prensa.


Red Hat y JBoss son marcas comerciales de Red Hat, Inc. registradas en los EE. UU. y en otros países. Linux® es la marca comercial registrada de Linus Torvalds en los EE. UU. y en otros países.


El texto original en el idioma fuente de este comunicado es la versión oficial autorizada. Las traducciones solo se suministran como adaptación y deben cotejarse con el texto en el idioma fuente, que es la única versión del texto que tendrá un efecto legal.


Linux/Open Source News Headlines – Yahoo! News


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Cold Remedy Cocktails: Do They Work?












Dec 8, 2012 8:00am



fd033  gty hot toddy cold nt 121207 wblog Cold Remedy Cocktails: Do They Work?

Credit: Getty Images













When it comes to adding a shot of alcohol to your cold or flu remedy, it’s hard not to wish those boozy concoctions are doing some good for your health.  As it turns out, they are.


Well, kinda.


Drinks like hot toddies, which traditionally contain whiskey, lemon and honey, can actually give cold and flu patients relief from their symptoms, said Dr. William Schaffner, chair of preventive medicine at Vanderbilt University Medical Center in Nashville, Tenn.


It just can’t prevent or cure a cold or flu virus.


“It would not have an effect on the virus itself, but its effect on the body can possibly give you some modest symptom relief,” Schaffner said. “The alcohol dilates blood vessels a little bit, and that makes it easier for your mucus membranes to deal with the infection.”


Since Sept. 30, more than 5,100 influenza cases have been reported to the Centers for Disease Control and Prevention, including 40 cases of H1N1.


Click here to read about how flu has little to do with cold weather.


Schaffner said warm moisture from a steaming mug of any beverage can offer symptom relief.


“That’s part of why chicken soup is thought to work,” he said.


Any liquid is good, but people drinking spiked remedies need to be sure they’re also keeping up their nonalcoholic fluids, Schaffner said. Alcohol, coffee and tea are diuretics, meaning they cause kidneys to get rid of fluid faster than they usually do.  Schaffner recommends supplementing that flu cocktail with water and fruit juice (as long as it’s not too sugary).


A Japanese study this week found that an ingredient in beer can curb the respiratory syncytial virus, which causes cold- and flu-like symptoms, according to The Associated Press. The study, funded by Sapporo Breweries, found that humulone, a chemical in hops,  can fight viruses. However, someone would have to drink 30 12-ounce cans of beer for it to work.


“We would not recommend going out and drinking 30 bottles of beer every day to ward off the flu,” Schaffner said. “Better to get vaccinated.”


Click here to read about five more flu-fighters.



SHOWS: Good Morning America

Health News Headlines – Yahoo! News


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Starbucks tax protest ‘under way’















Danni Wright, UK Uncut: “Starbucks should be paying the appropriate amount”



Tax avoidance campaigners say they are protesting at Starbucks cafes across the UK, despite the firm’s pledge to pay millions of pounds of extra corporation tax for the next two years.


The organisers, UK Uncut, say the coffee company’s promise to pay £20m is “a desperate attempt to deflect public pressure” from itself.


Starbucks said it had offered to meet protesters to “discuss their concerns”.


Starbucks’ “flagship” store in central London was said to be virtually empty.


UK Uncut said it was also highlighting the impact of government cuts on women, and planned to transform at least 40 Starbucks stores into “refuges, crèches and homeless shelters”.


BBC political correspondent Ben Geoghegan said the Starbucks “flagship” store in Conduit Street, central London, had been “virtually empty” following protests.


He said about 60 or so protesters were now thought to be heading to another Starbucks branch nearby.


UK Uncut said it had already heard from demonstrators gathering at ten outlets in London, Birmingham, Oxford and Nottingham.


Staff at the coffee chains were not being targeted, they added.


‘Tip of the iceberg’


UK Uncut spokeswoman Anna Walker said: “What Starbucks has done is offer a £20m PR stunt that’s coming straight out of their marketing budget.


“They haven’t offered or committed in any way to change the way they deal with their tax affairs in the UK or globally.”


“Starbucks is the tip of the iceberg when it comes to multinational companies tax avoidance – what we want to do is see the government clamping down on tax avoidance in a very real way.”


She added the government’s failure to recoup tax from such companies was leading to harmful austerity.


In a statement, a Starbucks spokesperson said: “Our highest priority is and remains the safety of our customers and employees. We trust that UK Uncut will respect it.


“We offered to meet with UK Uncut to discuss their concerns and make the protest a safe event for all involved. This invitation remains open.”


It added the company had “listened to our customers” and was “making a number of changes in our business to ensure we pay corporation tax in the UK” – something it urged UK Uncut and other concerned parties to “carefully consider”.


‘Unprecedented’


On Thursday, Starbucks revealed it would pay “a significant amount of tax during 2013 and 2014 regardless of whether the company is profitable during these years”.


The company has faced increasing public anger over its tax affairs, with some calling for a boycott of its outlets.


The company paid just £8.6m in corporation tax in its 14 years of trading in the UK, and nothing in the last three years – despite UK sales of nearly £400m in 2011.


Starbucks now says it expects to pay around £10m in corporation tax for each of the next two years, a move described by tax experts as unprecedented.


Speaking to BBC Radio 4′s Today programme, Exchequer Secretary to the Treasury David Gauke said HM Revenue and Customs must deal with all tax payers even-handedly.


He said: “If a taxpayer wants to pay more than is required under the law then that is really a matter for them. It’s a voluntary donation really rather than tax.”


BBC News – Business


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Election underscores Ghana’s democratic reputation












ACCRA, Ghana (AP) — Voters in Ghana selected their next president Friday in a ballot expected to mark the sixth transparent election in this West African nation, known as a beacon of democracy in a tumultuous region.


Proud of their democratic heritage, residents of this balmy, seaside capital trudged to the polls more than four hours before the sun was even up, standing inches apart in queues that in some places stretched 1,000-people deep.












By afternoon, some voters were getting agitated, after hitches with the use of a new biometric system caused delays at numerous polling stations.


Each polling station had a single biometric machine, and if it failed to identify the voter’s fingerprint, or if it broke down, there was no backup. At one polling station where the machine had broken down, a local chief said he’d barely moved a few inches: “I’m 58 years old, and I’ve been standing in this queue all day,” Nana Owusu said. “It’s not good.”


Late Friday, when it became clear that large numbers of people had not been able to vote, the election commission announced it would extend voting by a second day. This nation of 25 million is, however, deeply attached to its tradition of democracy, and voters were urging each other to remain calm while they waited their turn to choose from one of eight presidential contenders, including President John Dramani Mahama and his main challenger, Nana Akufo-Addo. The election commission


“Elections remind us how young our democracy is, how fragile it is,” said author Martina Odonkor, 44. “I think elections are a time when we all lose our cockiness about being such a shining light of democracy in Africa, and we start to get a bit nervous that things could go back to how they used to be.”


Ghana was once a troubled nation that suffered five coups and decades of stagnation, before turning a corner in the 1990s. It is now a pacesetter for the continent’s efforts to become democratic. No other country in the region has had so many elections deemed free and fair, a reputation voters hold close to their hearts.


The incumbent Mahama, a former vice president, was catapulted into office in July after the unexpected death of former President John Atta Mills. Before becoming vice president in 2009, the 54-year-old served as a minister and a member of parliament. He’s also written an acclaimed biography, recalling Ghana’s troubled past, called “My First Coup d’Etat.”


Akufo-Addo is a former foreign minister and the son of one of Ghana’s previous presidents. In 2008, Akufo-Addo lost the last presidential election to Mills by less than 1 percent during a runoff vote. Both candidates are trying to make the case that they will use the nation’s oil riches to help the poor.


Besides being one of the few established democracies in the region, Ghana also has the fastest-growing economy. But a deep divide still exists between those benefiting from the country’s oil, cocoa and mineral wealth and those left behind financially.


A group of men who had just voted gathered at a small bar a block away from a polling station in the middle class neighborhood of South Labadi. Danny Odoteye, 36, who runs the bar, said that the country’s economic progress is palpable and that the ruling party, and its candidate, are responsible for ushering in a period of growth.


“I voted for John Mahama,” he said. “Ghana is a prosperous country. Everything is moving smoothly.”


Administrator Victor Nortey, sitting on a plastic chair across from him, disagreed, saying the country’s newfound oil wealth should have resulted in more change.


“I voted for Nana Akufo-Addo,” He said. “Now we have oil. What is Mahama doing with the oil money?” Nortey said. “We can use that money to build schools.”


In an interview on the eve of the vote, Akufo-Addo told The Associated Press that the first thing he will do if elected is begin working on providing free high school education for all. “It’s a matter of great concern to me,” he said, adding that he plans to use the oil wealth to educate the population, industrialize the economy and create better jobs for Ghanaians.


Policy-oriented and intellectual, Akufo-Addo is favored by the young and urbanized voters. He was educated in England and comes from a privileged family. The ruling party has depicted him as elitist.


“The idea that merely because you are born into privilege that automatically means you are against the welfare of the ordinary people, that’s nonsense,” he said.


Ghana had one of the fastest growing economies in the world in 2011. Oil was discovered in 2007 and the country began producing it in December 2010.


Throughout the capital, new condominiums are rising up next to slums and luxury cars creep along narrow alleys lined with open sewers. A mall downtown features a Western-style cinema and is packed on weekends with middle class families. At the same time shantytowns are cropping up, packed with the urban poor.


Polls show that voters are almost evenly split over who can best deliver on the promise of development.


Kojo Mabwa said that he is voting for Akufo-Addo, because he is impressed by his promise of free education. He dismissed critics that say the project is too ambitious. “There is money,” he said. “(The ruling party) has done nothing for us. They are misusing our money.”


Paa Kwesi, a 30-year-old systems analyst, said he doesn’t think Akufo-Addo is making promises he can keep.


“He says he can do free education, but you have to crawl before you can walk. It’s not possible,” he said.


__


Associated Press writer Francis Kokutse contributed to this report from Accra, Ghana.


Africa News Headlines – Yahoo! News


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H&R Block, Zynga, Akamai are big market movers












NEW YORK (AP) — Stocks that moved substantially or traded heavily Thursday on the New York Stock Exchange and Nasdaq Stock Market:


NYSE












H&R Block Inc., up 89 cents at $ 18.26


The tax preparer’s quarterly loss narrows, helped by cost cuts. It thinks earnings will grow in the upcoming U.S. tax season.


SAIC Inc., down 41 cents at $ 11.26


The defense contractor’s quarterly earnings fall short of Wall Street expectations, and it’s eliminating 700 jobs to cut costs.


Men’s Wearhouse Inc., down 84 cents at $ 30.51


The men’s clothing store chain cuts its outlook, saying traffic dropped in November and it was more cautious about the rest of the year.


Safeway Inc., up 42 cents at $ 17.88


The grocery store chain moves up payment of its quarterly dividend to December from January to avoid potentially higher taxes.


Nasdaq


Zynga Inc., up 17 cents at $ 2.49


The troubled online games maker’s filing with a Nevada regulator could pave the way for it to enter the lucrative U.S. gambling market.


Vera Bradley Inc., down $ 3.07 at $ 23.14


The handbag maker’s forecast for the current quarter comes in short of Wall Street analysts’ average estimate.


Akamai Technologies Inc., up $ 3.56 at $ 39.06


The company, whose products help deliver online content, strikes a deal to provide services to AT&T customers.


Epoch Investment Partners Inc., up $ 5.78 at $ 27.69


Canada’s TD Bank plans to buy the U.S. asset manager for $ 668 million, a 28 percent premium from Wednesday’s closing price.


Gaming News Headlines – Yahoo! News


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Brazil government denies media reports of 2010 mad cow case












SAO PAULO (Reuters) – Brazil‘s Agriculture Ministry said on Friday that the country had registered no cases of mad cow disease, denying reports on some local media websites that said the disease had cropped up in the southern state of Parana two years ago.


In a statement on its website, the ministry said a cow that died in Parana in 2010 had tested positive for prions, the proteins believed to cause bovine spongiform encephalopathy, as the disease is formally called.












But the statement went on to say that the animal did not die of BSE and did not have symptoms of the disease.


“The World Animal Health Organization (OIE) in an official communication maintains the classification of Brazil as a country with insignificant risk of BSE,” the statement said.


In 2010, the ministry had also denied reports of a case of mad cow disease after news agencies picked up on the story. The government said it would provide further details on the case later on Friday at a news conference.


A story posted on the website of financial newspaper Valor Economico early on Friday said the cow in Parana had probably died of mad cow disease.


The outbreak of mad cow disease in Europe, North America and Japan a decade ago prompted beef importers to embargo shipments and caused temporary chaos in the industry. Brazil is the world’s largest beef exporter.


(Reporting by Reese Ewing and Gustavo Bonato; Editing by Lisa Von Ahn)


Health News Headlines – Yahoo! News


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Sharp fall in UK factory output













UK manufacturing output registered a surprisingly sharp fall in October, resurrecting fears of recession.












Output fell by 1.3% from September, the Office for National Statistics said, with food and drink output, notably beer, down following the Olympics.


It was the worst fall since June, when activity was depressed by extra public holidays for the Diamond Jubilee.


It also adds to evidence that the UK economy may be relapsing into recession after a short rebound over the summer.


The ONS’s latest growth estimate suggested the economy expanded 1% in the third quarter of the year, following nine months of mild contraction – in part thanks to the boost from tourist spending during the Summer Olympics.


Guns, beer, coke and drugs


Compared with a year ago, manufacturing output in October was down by 2.1%.


Production of alcoholic beverages was down 10% from September, and 16% from a year earlier.


There were also sharp falls in activity in the coke and refined petroleum, weapons and ammunitions, and pharmaceuticals sectors.


The figure for the wider measure of industrial output, which also includes energy production and mining, was down 0.8% in October, after falling 2.1% in September.


The seasonally adjusted index of production fell by 3% in October 2012 compared with a year ago, the 19th consecutive monthly fall on the same month a year ago.


The figures were worse than economists had expected.


“Very disappointing – triple dip [recession] here we come,” said Alan Clarke at Scotiabank.


“Manufacturing was diabolical. Sadly, I think there is not a lot to suggest that it is temporary. Survey data has been fairly downbeat.”


Potential


The chief economist at the British Chambers of Commerce, David Kern, said the industrial production figures were “bleak”, and added it was clear that “the manufacturing sector is facing major obstacles to a sustainable recovery”.


However, he said there were reasons to be confident about the sector’s prospects.


“Manufacturing is still a significant sector of our economy and is still benefitting from a competitive exchange rate, not withstanding sterling’s rise over the past year… the sector is well-managed, and has the potential to recover.”


Oil and gas extraction fell in the month at the fastest rate since records began in January 1998, although that was partly due to maintenance works, which included the temporary shutdown of the largest oil field in the North Sea.


The news comes in the same week as the government’s Autumn Statement, which said the economy would shrink this year, rather than expand, as had first been predicted.


BBC News – Business


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